Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20421536 | 1.00 | KMT2A (0.43) | KMT2ASMN1; SMN2STAT3CYP2C19KEAP1 | |
| SCHEMBL3598688 | 0.88 | KMT2A (0.50) | KMT2ASMN1; SMN2STAT3CYP2C19KEAP1 | |
| SCHEMBL18213 | 0.88 | KMT2A (0.54) | KMT2ASMN1; SMN2STAT3CYP2C19KEAP1 | |
| SCHEMBL17902 | 0.87 | KMT2A (0.53) | KMT2ASMN1; SMN2STAT3CYP2C19KEAP1 | |
| SCHEMBL16641783 | 0.85 | KMT2A (0.49) | KMT2ASMN1; SMN2STAT3CYP2C19GAA | |
| SCHEMBL17386324 | 0.78 | KMT2A (0.42) | KMT2ASMN1; SMN2STAT3CYP2C19GAA | |
| SCHEMBL17005 | 0.78 | KMT2A (0.42) | KMT2ASMN1; SMN2STAT3CYP2C19GAA | |
| SCHEMBL10171744 | 0.78 | CYP3A4 (0.48) | KMT2ASMN1; SMN2STAT3CYP2C19GAA | |
| SCHEMBL17525344 | 0.78 | ALDH1A1 (0.41) | KMT2ASMN1; SMN2CYP2C19ALDH1A1POLB | |
| SCHEMBL17385962 | 0.77 | KMT2A (0.45) | KMT2ASMN1; SMN2STAT3CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200048407-A1 | TELECHELIC PREPOLYMERS AND REACTION PRODUCTS THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2020-02-13 | — | — | US | disclosed |
| US-20180215865-A1 | TELECHELIC PREPOLYMERS AND REACTION PRODUCTS THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-08-02 | — | — | US | disclosed |
| US-20180215865-A1 | TELECHELIC PREPOLYMERS AND REACTION PRODUCTS THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2018-08-02 | — | — | US | disclosed |
| WO-2017023506-A1 | TELECHELIC PREPOLYMERS AND REACTION PRODUCTS THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2017-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180215865-A1 | TELECHELIC PREPOLYMERS AND REACTION PRODUCTS THEREOF | DTYMK, DDOST, DDT | KMT2A 4178/4885SMN1; SMN2 3790/4885STAT3 4600/4885 |
| US-20200048407-A1 | TELECHELIC PREPOLYMERS AND REACTION PRODUCTS THEREOF | DTYMK, DDOST, DDT | KMT2A 4178/4885SMN1; SMN2 3790/4885STAT3 4600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.