Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.66 |
| ▸ | KDR | P35968 | 18/20 | 0.66 |
| ▸ | MST1R | Q04912 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18487296 | 0.94 | MET (0.75) | METKDRMST1R | |
| SCHEMBL18487293 | 0.92 | MET (0.68) | METKDRMST1R | |
| SCHEMBL307602 | 0.90 | MET (0.64) | METKDRMST1R | |
| SCHEMBL306334 | 0.89 | MET (0.66) | METKDRMST1R | |
| SCHEMBL307087 | 0.89 | MET (0.69) | METKDRMST1R | |
| SCHEMBL307609 | 0.88 | MET (0.65) | METKDRMST1R | |
| SCHEMBL307273 | 0.88 | MET (0.60) | METKDRMST1R | |
| SCHEMBL308135 | 0.88 | MET (0.59) | METKDRMST1R | |
| SCHEMBL895912 | 0.87 | MET (0.63) | METKDRMST1R | |
| SCHEMBL896234 | 0.87 | MET (0.76) | METKDRMST1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957498-B1 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | METHYLGENE INC (CA) | 2017-02-15 | — | — | EP | claimed |
| EP-1957498-B1 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | METHYLGENE INC (CA) | 2017-02-15 | — | — | EP | disclosed |