Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 10/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | YES1 | P07947 | 1/20 | 0.50 |
| ▸ | LYN | P07948 | 1/20 | 0.50 |
| ▸ | HCK | P08631 | 1/20 | 0.50 |
| ▸ | FGR | P09769 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.50 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.50 |
| ▸ | MST1R | Q04912 | 10/20 | 0.47 |
| ▸ | MET | P08581 | 9/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL895849 | 0.86 | KDR (0.63) | KDRLCKYES1LYNHCK | |
| SCHEMBL18487317 | 0.85 | MET (0.48) | KDRMST1RMET | |
| SCHEMBL308790 | 0.83 | MET (0.52) | KDRMST1RMET | |
| SCHEMBL306649 | 0.82 | KDR (0.42) | KDRMST1RMET | |
| SCHEMBL18487309 | 0.82 | MST1R (0.49) | KDRLCKYES1LYNHCK | |
| SCHEMBL306601 | 0.81 | MET (0.48) | KDRMST1RMET | |
| SCHEMBL18516648 | 0.80 | MST1R (0.56) | KDRLCKYES1LYNHCK | |
| SCHEMBL18487299 | 0.80 | MET (0.65) | KDRMST1RMET | |
| SCHEMBL308496 | 0.80 | MET (0.50) | KDRMST1RMET | |
| SCHEMBL895974 | 0.80 | KDR (0.65) | KDRLCKYES1LYNHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957498-B1 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | METHYLGENE INC (CA) | 2017-02-15 | — | — | EP | disclosed |