Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MST1R | Q04912 | 5/20 | 0.49 |
| ▸ | MET | P08581 | 13/20 | 0.48 |
| ▸ | KDR | P35968 | 11/20 | 0.48 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 2/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | STK25 | O00506 | 1/20 | 0.41 |
| ▸ | CIT | O14578 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | MUSK | O15146 | 1/20 | 0.41 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAP3K13 | O43283 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308625 | 0.88 | MET (0.48) | MST1RMETKDR | |
| SCHEMBL306601 | 0.87 | MET (0.48) | MST1RMETKDR | |
| SCHEMBL896686 | 0.86 | MET (0.64) | MST1RMETKDRFLT3 | |
| SCHEMBL308790 | 0.85 | MET (0.52) | MST1RMETKDR | |
| SCHEMBL18487298 | 0.84 | MET (0.50) | MST1RMETKDR | |
| SCHEMBL307198 | 0.83 | MET (0.49) | MST1RMETKDR | |
| SCHEMBL307771 | 0.83 | MET (0.44) | MST1RMETKDRFLT3FLT1 | |
| SCHEMBL18487307 | 0.82 | KDR (0.50) | MST1RMETKDRFLT3LCK | |
| SCHEMBL307498 | 0.82 | MET (0.51) | MST1RMETKDR | |
| SCHEMBL308309 | 0.81 | MET (0.66) | MST1RMETKDRAURKAFPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957498-B1 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | METHYLGENE INC (CA) | 2017-02-15 | — | — | EP | disclosed |