Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 16/20 | 0.59 |
| ▸ | CLK3 | P49761 | 16/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 16/20 | 0.59 |
| ▸ | WNT1 | P04628 | 2/20 | 0.57 |
| ▸ | ITK | Q08881 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18485356 | 0.91 | CLK2 (0.65) | CLK2CLK3DYRK1AWNT1 | |
| SCHEMBL18488102 | 0.90 | CLK2 (0.65) | CLK2CLK3DYRK1AITK | |
| SCHEMBL18446253 | 0.90 | WNT1 (0.70) | CLK2CLK3DYRK1AWNT1ITK | |
| SCHEMBL18484683 | 0.90 | CLK2 (0.51) | CLK2CLK3DYRK1AWNT1ITK | |
| SCHEMBL18494677 | 0.88 | CLK2 (0.69) | CLK2CLK3DYRK1AWNT1 | |
| SCHEMBL18487109 | 0.87 | CLK2 (0.71) | CLK2CLK3DYRK1AWNT1ITK | |
| SCHEMBL18489999 | 0.86 | CLK3 (0.70) | CLK2CLK3DYRK1AWNT1 | |
| SCHEMBL18447282 | 0.85 | CLK2 (0.68) | CLK2CLK3DYRK1AWNT1ITK | |
| SCHEMBL18484733 | 0.84 | CLK3 (0.58) | CLK2CLK3DYRK1AWNT1 | |
| SCHEMBL18487120 | 0.84 | CLK2 (0.61) | CLK2CLK3DYRK1AWNT1ITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017023986-A1 | 3-(1H-INDOL-2-YL)-1H-INDAZOLES AND THERAPEUTIC USES THEREOF | SAMUMED, LLC (US) | 2017-02-09 | — | — | WO | disclosed |