SCHEMBL18488019

SCHEMBL18488019

CC1(C)OB(c2ccc3c(c2)C(c2ccccc2)c2cc(B4OC(C)(C)C(C)(C)O4)ccc2C=C3)OC1(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 12/20 0.47
LPL P06858 11/20 0.47
P4HB P07237 1/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
CA12 O43570 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
F11 P03951 2/20 0.35
F2 P00734 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
ROCK1 Q13464 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12873509 0.87 LIPG (0.51) LIPGLPLP4HBCA1CA2
SCHEMBL16282601 0.85 LIPG (0.50) LIPGLPLP4HBCA1CA2
SCHEMBL23567924 0.75 LIPG (0.51) LIPGLPLP4HBCA1CA2
SCHEMBL1932321 0.73 LIPG (0.43) LIPGLPLP4HBROCK1DGAT1
SCHEMBL1932318 0.73 LIPG (0.43) LIPGLPLP4HBROCK1DGAT1
SCHEMBL1932319 0.73 LIPG (0.43) LIPGLPLP4HBROCK1DGAT1
SCHEMBL20696834 0.72 LPL (0.51) LIPGLPLP4HBCA1CA2
SCHEMBL19861982 0.72 LIPG (0.65) LIPGLPLP4HBCA1CA2
SCHEMBL27026508 0.71 LIPG (0.63) LIPGLPLP4HBCA1CA2
SCHEMBL17072973 0.71 GAA (0.48) LIPGLPLP4HBCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10193083-B2 Spirally configured cis-stilbene/fluorene hybrid compounds and organic light emitting device comprising the same NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2019-01-29 US disclosed
US-20170040547-A1 SPIRALLY CONFIGURED CIS-STILBENE/FLUORENE HYBRID COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2017-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170040547-A1 SPIRALLY CONFIGURED CIS-STILBENE/FLUORENE HYBRID COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME SLCO2B1, SLCO4C1, SLCO1B1 LIPG 3134/4885LPL 1667/4885P4HB 2927/4885
US-10193083-B2 Spirally configured cis-stilbene/fluorene hybrid compounds and organic light emitting device comprising the same SLCO2B1, SLCO4C1, SLCO1B1 LIPG 3134/4885LPL 1667/4885P4HB 2927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.