SCHEMBL18489505

SCHEMBL18489505

CCCCC1C(C(C)C)=Cc2ccc(C(C)C)cc21

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RORA P35398 1/20 0.31
RORC P51449 1/20 0.31
RORB Q92753 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1454072 0.76 LMNA (0.36)
SCHEMBL18489608 0.69 HTT (0.30)
SCHEMBL1452984 0.67 HTR2A (0.39)
SCHEMBL4650959 0.65 LMNA (0.37)
SCHEMBL1452774 0.63 LMNA (0.35)
SCHEMBL1452810 0.63 HTR2A (0.35)
SCHEMBL19126163 0.58 LMNA (0.40)
SCHEMBL812811 0.58 CYP3A4 (0.44)
Hydrochloric Acid SCHEMBL812262 0.57 KDM4E (0.45)
SCHEMBL8854185 0.56 CYP3A4 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3135699-B1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-07-21 EP claimed
US-10184017-B2 Catalyst component for propene polymerization, preparation method thereof, and catalyst containing the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-01-22 US claimed
CN-105085730-B It is a kind of for the catalytic component of olefinic polymerization, preparation method and its catalyst 中国石油化工股份有限公司 2018-12-28 CN claimed
EP-3135699-A1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME China Petroleum & Chemical Corporation (CN) 2017-03-01 EP claimed
US-20170044280-A1 Catalyst Component for Propene Polymerization, Preparation Method Thereof, and Catalyst Containing the Same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-02-16 US claimed
EP-3135699-B1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-07-21 EP disclosed
US-10184017-B2 Catalyst component for propene polymerization, preparation method thereof, and catalyst containing the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-01-22 US disclosed
CN-105085730-B It is a kind of for the catalytic component of olefinic polymerization, preparation method and its catalyst 中国石油化工股份有限公司 2018-12-28 CN disclosed
EP-3135699-A1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME China Petroleum & Chemical Corporation (CN) 2017-03-01 EP disclosed
US-20170044280-A1 Catalyst Component for Propene Polymerization, Preparation Method Thereof, and Catalyst Containing the Same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-02-16 US disclosed