Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1453706 | 0.77 | LMNA (0.36) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL4651925 | 0.76 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL1452652 | 0.76 | LMNA (0.35) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL1452774 | 0.76 | LMNA (0.35) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL6266174 | 0.75 | HTR2A (0.34) | LMNAALDH1A1ALOX12 | |
| SCHEMBL4652087 | 0.75 | L3MBTL1 (0.32) | LMNAGAAHTT | |
| SCHEMBL4652089 | 0.72 | QDPR (0.35) | LMNA | |
| SCHEMBL4651188 | 0.71 | CYP3A4 (0.35) | — | |
| SCHEMBL4651917 | 0.69 | HDAC2 (0.40) | PTGS1 | |
| SCHEMBL4650927 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971621-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | ExxonMobil Chemical Patents Inc. (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007070045-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |