Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL595764 | 0.81 | PTPN11 (0.59) | LGMNALDH1A1NPC1MAPTKMT2A | |
| SCHEMBL3772589 | 0.81 | SMN1; SMN2 (0.68) | ALDH1A1MAPTKMT2APOLBSMN1; SMN2 | |
| SCHEMBL3766900 | 0.80 | KDM4E (0.54) | F10CYP2C19 | |
| SCHEMBL595334 | 0.78 | SHMT2 (0.59) | LGMNALDH1A1MAPTKMT2APOLB | |
| SCHEMBL16323911 | 0.77 | ALDH1A1 (0.67) | LGMNALDH1A1NPC1MAPTKMT2A | |
| SCHEMBL1024938 | 0.76 | SMN1; SMN2 (0.47) | LGMNALDH1A1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL2574241 | 0.76 | ALDH1A1 (0.54) | LGMNALDH1A1NPC1MAPTKMT2A | |
| SCHEMBL195417 | 0.76 | KDM4E (0.60) | ALDH1A1MAPTKMT2ARAB9APOLB | |
| SCHEMBL20564967 | 0.75 | PTPN11 (0.53) | LGMNALDH1A1MAPTKMT2ARAB9A | |
| SCHEMBL3786436 | 0.75 | KMT2A (0.55) | LGMNALDH1A1NPC1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402327-B1 | Acetamide compounds as glucokinase activators, their process and medicinal applications | IMPETIS BIOSCIENCES LTD (IN) | 2018-03-07 | — | — | EP | disclosed |
| EP-2402327-A1 | Acetamide compounds as glucokinase activators, their process and medicinal applications | Advinus Therapeutics Private Limited (IN) | 2012-01-04 | — | — | EP | disclosed |