Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL328090 | 0.86 | MEN1 (0.38) | MEN1KMT2ATDP1 | |
| SCHEMBL17831505 | 0.81 | MEN1 (0.61) | MEN1KMT2ATDP1 | |
| SCHEMBL4417153 | 0.80 | MEN1 (0.70) | MEN1KMT2ATDP1 | |
| SCHEMBL10428033 | 0.80 | MEN1 (0.70) | MEN1KMT2ATDP1 | |
| SCHEMBL4411639 | 0.77 | MEN1 (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL419298 | 0.77 | MEN1 (0.43) | MEN1KMT2ATDP1 | |
| SCHEMBL3458732 | 0.76 | MEN1 (0.39) | MEN1KMT2ATDP1 | |
| SCHEMBL112086 | 0.76 | MEN1 (0.39) | MEN1KMT2ATDP1 | |
| SCHEMBL1608601 | 0.76 | MEN1 (0.39) | MEN1KMT2ATDP1 | |
| SCHEMBL21851606 | 0.76 | MEN1 (0.53) | MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3334801-B1 | MATERIAL COMBINATION | MERCK PATENT GMBH (DE) | 2020-05-27 | — | — | EP | disclosed |
| US-20180237696-A1 | MATERIAL COMBINATION | MERCK PATENT GMBH (DE) | 2018-08-23 | — | — | US | disclosed |
| EP-3334801-A1 | MATERIAL COMBINATION | Merck Patent GmbH (DE) | 2018-06-20 | — | — | EP | disclosed |
| WO-2017025167-A1 | MATERIAL COMBINATION | MERCK PATENT GMBH (DE) | 2017-02-16 | — | — | WO | disclosed |