SCHEMBL328090

SCHEMBL328090

CC1(F)C(F)(F)C2(F)C(F)(F)C(F)(F)C1(F)C2(F)F

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18496397 0.89 MEN1 (0.40) MEN1KMT2ATDP1
SCHEMBL18496402 0.86 MEN1 (0.47) MEN1KMT2ATDP1
SCHEMBL4411639 0.85 MEN1 (0.33) MEN1KMT2ATDP1
SCHEMBL419298 0.85 MEN1 (0.43) MEN1KMT2ATDP1
SCHEMBL245162 0.76
SCHEMBL11613184 0.76 MEN1 (0.44) MEN1KMT2ATDP1
SCHEMBL17831505 0.74 MEN1 (0.61) MEN1KMT2ATDP1
SCHEMBL10706294 0.71 MEN1 (0.57) MEN1KMT2ATDP1
SCHEMBL9451902 0.71 MEN1 (0.57) MEN1KMT2ATDP1
SCHEMBL10428033 0.71 MEN1 (0.70) MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120065347-A1 FLUOROCOMPOUND HAVING HIGHLY FLUORINATED NORBORNANE STRUCTURE, FLUOROPOLYMER, AND THEIR PRODUCTION PROCESSES ASAHI GLASS COMPANY LIMITED (JP) 2012-03-15 US disclosed
US-20120065347-A1 FLUOROCOMPOUND HAVING HIGHLY FLUORINATED NORBORNANE STRUCTURE, FLUOROPOLYMER, AND THEIR PRODUCTION PROCESSES ASAHI GLASS COMPANY LIMITED (JP) 2012-03-15 US disclosed
US-8134033-B2 Fluorocompound having highly fluorinated norbornane structure, fluoropolymer, and their production processes ASAHI GLASS COMPANY, LIMITED (JP) 2012-03-13 US disclosed
US-7825275-B2 Fluorinated compound, fluoropolymer and method for producing the compound ASAHI GLASS COMPANY, LIMITED (JP) 2010-11-02 US disclosed
US-20100016532-A1 NOVEL FLUORINATED COMPOUND, FLUOROPOLYMER AND METHOD FOR PRODUCING THE COMPOUND ASAHI GLASS COMPANY, LIMITED (JP) 2010-01-21 US disclosed
US-20090192330-A1 FLUOROCOMPOUND HAVING HIGHLY FLUORINATED NORBORNANE STRUCTURE, FLUOROPOLYMER, AND THEIR PRODUCTION PROCESSES ASAHI GLASS COMPANY, LIMITED (JP) 2009-07-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120065347-A1 FLUOROCOMPOUND HAVING HIGHLY FLUORINATED NORBORNANE STRUCTURE, FLUOROPOLYMER, AND THEIR PRODUCTION PROCESSES PFAS, AFF1, CYP1B1 MEN1 344/4885KMT2A 2427/4885TDP1 1260/4885
US-20100016532-A1 NOVEL FLUORINATED COMPOUND, FLUOROPOLYMER AND METHOD FOR PRODUCING THE COMPOUND CBR3, CBR1, AFF2 MEN1 1161/4885KMT2A 1081/4885TDP1 4353/4885
US-20090192330-A1 FLUOROCOMPOUND HAVING HIGHLY FLUORINATED NORBORNANE STRUCTURE, FLUOROPOLYMER, AND THEIR PRODUCTION PROCESSES CWC22, PARP2, AFF2 MEN1 1037/4885KMT2A 776/4885TDP1 1885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.