Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18496651 | 0.84 | KDM4E (0.48) | MAPTGPR35L3MBTL1KDM4EHTT | |
| SCHEMBL18496650 | 0.83 | PPARA (0.42) | MAPTPPARAGPR35L3MBTL1KDM4E | |
| SCHEMBL25096343 | 0.78 | MAPT (0.50) | MAPTPPARAL3MBTL1KDM4EHTT | |
| SCHEMBL461099 | 0.77 | MAPT (0.69) | MAPTL3MBTL1KDM4EHTTPKM | |
| SCHEMBL7686855 | 0.77 | MAPT (0.67) | MAPTPPARAGPR35L3MBTL1KDM4E | |
| SCHEMBL10005935 | 0.75 | MAPT (0.72) | MAPTL3MBTL1KDM4EHTTPKM | |
| SCHEMBL3901240 | 0.74 | PPARA (0.49) | MAPTPPARAL3MBTL1KDM4EHTT | |
| SCHEMBL13738586 | 0.73 | CCR1 (0.52) | MAPTPKMLMNAKMT2AALDH1A1 | |
| SCHEMBL9732129 | 0.71 | MAPT (0.61) | MAPTL3MBTL1KDM4EHTTPKM | |
| SCHEMBL29410744 | 0.71 | MAPT (0.61) | MAPTL3MBTL1KDM4EHTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017025493-A1 | QUINOLINE EZH2 INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | WO | disclosed |
| WO-2017025493-A1 | QUINOLINE EZH2 INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | WO | disclosed |