SCHEMBL461099

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10005935	0.93	MAPT (0.72)	MAPTL3MBTL1CRHR1LMNANR4A2
	SCHEMBL20561879	0.90	MAPT (0.64)	MAPTL3MBTL1CRHR1LMNANR4A2
	SCHEMBL30009397	0.90	MAPT (0.64)	MAPTL3MBTL1CRHR1LMNANR4A2
	SCHEMBL29410744	0.87	MAPT (0.61)	MAPTL3MBTL1CRHR1LMNANR4A2
	SCHEMBL9732129	0.87	MAPT (0.61)	MAPTL3MBTL1CRHR1LMNANR4A2
	SCHEMBL28755579	0.85	MAPT (0.58)	MAPTL3MBTL1CRHR1LMNANR4A2
	SCHEMBL3063558	0.83	NR4A2 (0.71)	MAPTL3MBTL1CRHR1LMNANR4A2
	SCHEMBL10700262	0.83	MAPT (0.62)	MAPTL3MBTL1CRHR1LMNANR4A2
	SCHEMBL15983186	0.82	MAPT (0.60)	MAPTL3MBTL1CRHR1LMNANR4A2
	SCHEMBL2811314	0.82	MAPT (0.64)	MAPTL3MBTL1CRHR1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.