Sugi Predict

Sugi Predict / Compounds / SCHEMBL9732129

SCHEMBL9732129

SCHEMBL9732129

Cc1cc(Cl)c2ccc(Cl)c(Cl)c2n1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.61
▸ L3MBTL1 Q9Y468 1/20 0.61
▸ CRHR1 P34998 2/20 0.49
▸ LMNA P02545 1/20 0.47
▸ NR4A2 P43354 5/20 0.43
▸ KDM4E B2RXH2 4/20 0.41
▸ HTT P42858 2/20 0.41
▸ PKM P14618 1/20 0.41
▸ KMT2A Q03164 2/20 0.39
▸ POLB P06746 1/20 0.39
▸ GAA P10253 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ ADORA1 P30542 1/20 0.37
▸ CD38 P28907 1/20 0.36
▸ KCNH2 Q12809 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29410744 1.00 MAPT (0.61) MAPTL3MBTL1CRHR1LMNANR4A2
SCHEMBL461099 0.87 MAPT (0.69) MAPTL3MBTL1CRHR1LMNANR4A2
SCHEMBL10005935 0.85 MAPT (0.72) MAPTL3MBTL1CRHR1LMNANR4A2
SCHEMBL22710270 0.84 MAPT (0.68) MAPTL3MBTL1CRHR1LMNANR4A2
SCHEMBL439768 0.83 NR4A2 (0.65) MAPTL3MBTL1CRHR1LMNANR4A2
SCHEMBL26215435 0.79 MAPT (0.39) MAPTL3MBTL1LMNAKDM4EHTT
SCHEMBL20561879 0.78 MAPT (0.64) MAPTL3MBTL1CRHR1LMNANR4A2
SCHEMBL30009397 0.78 MAPT (0.64) MAPTL3MBTL1CRHR1LMNANR4A2
SCHEMBL3063558 0.76 NR4A2 (0.71) MAPTL3MBTL1CRHR1LMNANR4A2
SCHEMBL15983186 0.76 MAPT (0.60) MAPTL3MBTL1CRHR1LMNANR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042737-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS IMMUNESENSOR THERAPEUTICS INC (US) 2026-02-12 — — US disclosed
US-12281078-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2025-04-22 — — US disclosed
US-20250115579-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2025-04-10 — — US disclosed
EP-4486734-A1 QUINOLINE CGAS ANTAGONIST COMPOUNDS Immunesensor Therapeutics, Inc. (US) 2025-01-08 — — EP disclosed
US-12134609-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-11-05 — — US disclosed
US-12091387-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-09-17 — — US disclosed
US-20240092760-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2024-03-21 — — US disclosed
US-11873291-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-01-16 — — US disclosed
US-11873291-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-01-16 — — US disclosed
US-11873291-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-01-16 — — US disclosed
US-20230357158-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2023-11-09 — — US disclosed
US-20230357158-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2023-11-09 — — US disclosed
WO-2023168367-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS IMMUNESENSOR THERAPEUTICS, INC. (US) 2023-09-07 — — WO disclosed
WO-2023168367-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS IMMUNESENSOR THERAPEUTICS, INC. (US) 2023-09-07 — — WO disclosed
EP-4208452-A1 QUINOLINE CGAS ANTAGONIST COMPOUNDS Immunesensor Therapeutics, Inc. (US) 2023-07-12 — — EP disclosed
CN-116234802-A Quinoline CGAS antagonist compounds 免疫传感器治疗股份有限公司 2023-06-06 — — CN disclosed
US-20230081291-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS IMMUNESENSOR THERAPEUTICS, INC. (US) 2023-03-16 — — US disclosed
US-5104884-A Rheumatic diseases, fungicides ALKALOIDA VEGYESZETI GYAR (HU) 1992-04-14 — — US disclosed
EP-0221947-A1 TRIAZOLYL QUINOLINE DERIVATIVES. ALKALOIDA VEGYESZETI GYAR (HU) 1987-05-20 — — EP disclosed
WO-1986006721-A1 TRIAZOLYL QUINOLINE DERIVATIVES ALKALOIDA VEGYÉSZETI GYÁR (HU) 1986-11-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115579-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS CGAS, GLS2, GLS MAPT 3235/4885L3MBTL1 4285/4885CRHR1 935/4885
US-12091387-B2 Quinoline cGAS antagonist compounds CGAS, GLS2, GLS MAPT 3235/4885L3MBTL1 4285/4885CRHR1 935/4885
US-20260042737-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS CGAS, SSB, NT5C2 MAPT 4745/4885L3MBTL1 3793/4885CRHR1 448/4885
US-20240092760-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS CGAS, GLS2, GLS MAPT 3235/4885L3MBTL1 4285/4885CRHR1 935/4885
US-11873291-B2 Quinoline cGAS antagonist compounds CGAS, GLS2, GLS MAPT 3235/4885L3MBTL1 4285/4885CRHR1 935/4885
US-12134609-B2 Quinoline cGAS antagonist compounds CGAS, GLS2, GLS MAPT 3235/4885L3MBTL1 4285/4885CRHR1 935/4885
US-20230357158-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS CGAS, GLS2, GLS MAPT 3235/4885L3MBTL1 4285/4885CRHR1 935/4885
US-12281078-B2 Quinoline cGAS antagonist compounds CGAS, GLS2, GLS MAPT 3235/4885L3MBTL1 4285/4885CRHR1 935/4885
US-20230081291-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS CGAS, GLS2, GLS MAPT 3235/4885L3MBTL1 4285/4885CRHR1 935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.