Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.72 |
| ▸ | CA1 | P00915 | 5/20 | 0.72 |
| ▸ | CA2 | P00918 | 5/20 | 0.72 |
| ▸ | CA7 | P43166 | 5/20 | 0.72 |
| ▸ | CA9 | Q16790 | 5/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.72 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 3/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939271 | 0.87 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL190719 | 0.86 | CA12 (0.72) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1147208 | 0.86 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29823214 | 0.86 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL603415 | 0.84 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17912414 | 0.84 | ESR1 (0.69) | CA12CA1CA2CA7CA9 | |
| SCHEMBL39791 | 0.84 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29625511 | 0.84 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4849260 | 0.84 | MAPT (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL12780972 | 0.83 | CA12 (0.57) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257355-A1 | HYDROXAMIC ACID-CONTAINING COMPOUND, AND PREPARATION METHOD AND USE THEREOF | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2023-08-17 | — | — | US | disclosed |
| WO-2021238328-A1 | COMPOUND CONTAINING HYDROXAMIC ACID, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2021-12-02 | — | — | WO | disclosed |
| US-20210171883-A1 | ANTIVIRAL WIPER | FUJIFILM CORPORATION (JP) | 2021-06-10 | — | — | US | disclosed |
| US-11020391-B2 | CRMP2 sumoylation inhibitors and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-06-01 | — | — | US | disclosed |
| CN-108289882-B | CRMP2 SUMO inhibitors and uses thereof | 代表亚利桑那大学的亚利桑那校董会 | 2020-12-29 | — | — | CN | disclosed |
| US-20200093822-A1 | CRMP2 SUMOYLATION INHIBITORS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2020-03-26 | — | — | US | disclosed |
| US-10441586-B2 | CRMP2 SUMOylation inhibitors and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2019-10-15 | — | — | US | disclosed |
| US-20180289700-A1 | CRMP2 SUMOYLATION INHIBITORS AND USES THEREOF | Arizona Board of Regents on Behalf of the University of Arzona (US) | 2018-10-11 | — | — | US | disclosed |
| EP-2402327-B1 | Acetamide compounds as glucokinase activators, their process and medicinal applications | IMPETIS BIOSCIENCES LTD (IN) | 2018-03-07 | — | — | EP | disclosed |
| EP-1781661-B1 | VASOPRESSIN V1A ANTAGONISTS | VANTIA LTD (GB) | 2017-06-07 | — | — | EP | disclosed |
| US-20060014945-A1 | N-((hetero)aryl)-N-(2-oxo-azepan-3-yl)-benzenesulfonamides; useful treating AD or common cancers by blocking the activity of gamma-secretase and reducing/preventing the formation of amyloidogenic Abeta peptides and by blocking the Notch signaling pathways that can interfere with cancer pathogenesis. | F. HOFFMANN-LA ROCHE AG (CH) | 2006-01-19 | — | — | US | disclosed |
| EP-1577288-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | Eisai Co., Ltd. (JP) | 2005-09-21 | — | — | EP | disclosed |
| US-20050113424-A1 | Novel arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD (JP) | 2005-05-26 | — | — | US | disclosed |
| WO-2005025554-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | JAPAN TOBACCO INC. (JP) | 2005-03-24 | — | — | WO | disclosed |
| EP-1481966-A1 | NOVEL ARYLAMIDINE DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-12-01 | — | — | EP | disclosed |
| US-4714774-A | ANTIASTHMATIC OR ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-12-22 | — | — | US | disclosed |
| EP-0181125-A2 | Benzoic acid derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0180416-A2 | Benzoic acid analogues and their production | Takeda Chemical Industries, Ltd. (JP) | 1986-05-07 | — | — | EP | disclosed |
| US-4077968-A | ANTIINFLAMMATORY, ANTIRHEUMATIC, ANALGESIC, ANTILIPEMIC | SHIONOGI & CO., LTD. (JA) | 1978-03-07 | — | — | US | disclosed |
| US-4025528-A | ANTIINFLAMMATORY, ANALGESIC, ANTILIPEMIC | SHIONOGI & CO., LTD. (JA) | 1977-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200093822-A1 | CRMP2 SUMOYLATION INHIBITORS AND USES THEREOF | SUMO2, SUMO1, SUMO3 | CA12 3870/4885CA1 2632/4885CA2 1518/4885 |
| US-20060014945-A1 | N-((hetero)aryl)-N-(2-oxo-azepan-3-yl)-benzenesulfonamides; useful treating AD or common cancers by blocking the activity of gamma-secretase and reducing/preventing the formation of amyloidogenic Abeta peptides and by blocking the Notch signaling pathways that can interfere with cancer pathogenesis. | BACE1, APP, BACE2 | CA12 3144/4885CA1 1569/4885CA2 2044/4885 |
| US-20050113424-A1 | Novel arylamidine derivative or salt thereof | SLC7A1, NAT1, NACA | CA12 3055/4885CA1 4424/4885CA2 1594/4885 |
| US-20210171883-A1 | ANTIVIRAL WIPER | CGAS, PRKX, PDE4C | CA12 2396/4885CA1 2414/4885CA2 1789/4885 |
| US-11020391-B2 | CRMP2 sumoylation inhibitors and uses thereof | SUMO2, SUMO1, SUMO3 | CA12 3870/4885CA1 2632/4885CA2 1518/4885 |
| US-20180289700-A1 | CRMP2 SUMOYLATION INHIBITORS AND USES THEREOF | SUMO1, SUMO2, SUMO3 | CA12 4529/4885CA1 3776/4885CA2 2745/4885 |
| US-20230257355-A1 | HYDROXAMIC ACID-CONTAINING COMPOUND, AND PREPARATION METHOD AND USE THEREOF | SI, SCD, SMPD1 | CA12 1023/4885CA1 122/4885CA2 406/4885 |
| US-10441586-B2 | CRMP2 SUMOylation inhibitors and uses thereof | SUMO1, SUMO2, SUMO3 | CA12 4529/4885CA1 3776/4885CA2 2745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.