SCHEMBL1850271

SCHEMBL1850271

C=CC(=O)OC(CC)CN=C=O

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3095028 0.86 TSHR (0.43) TSHRHPGD
SCHEMBL10412807 0.83 TSHR (0.44) TSHRHPGD
SCHEMBL561301 0.81 TSHR (0.45) TSHRHPGD
SCHEMBL30921626 0.81 TSHR (0.41) TSHRHPGD
SCHEMBL2830959 0.81 TSHR (0.40) TSHRHPGD
SCHEMBL28562465 0.80 TSHR (0.34) TSHRHPGD
SCHEMBL28217248 0.79 TSHR (0.33) TSHR
SCHEMBL8024857 0.79 TSHR (0.36) TSHR
SCHEMBL3669386 0.78 TSHR (0.38) TSHRHPGD
SCHEMBL28979328 0.77 TSHR (0.33) TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11891472-B2 Composition, production method for composition, and production method for unsaturated compound RESONAC CORPORATION (JP) 2024-02-06 US disclosed
EP-3842417-B1 COMPOSITION, PRODUCTION METHOD FOR COMPOSITION, AND PRODUCTION METHOD FOR UNSATURATED COMPOUND RESONAC CORP (JP) 2024-01-24 EP disclosed
CN-116583498-A Blocked isocyanate compound 株式会社力森诺科 2023-08-11 CN disclosed
US-11661474-B2 Composition, production method for composition, and production method for unsaturated compound SHOWA DENKO K.K. (JP) 2023-05-30 US disclosed
EP-3842414-B1 COMPOSITION, PRODUCTION METHOD FOR COMPOSITION, AND PRODUCTION METHOD FOR UNSATURATED COMPOUND SHOWA DENKO KK (JP) 2023-04-05 EP disclosed
CN-112533896-B Composition, method for producing composition, and method for producing unsaturated compound 昭和电工株式会社 2023-03-03 CN disclosed
EP-3842416-B1 COMPOSITION, PRODUCTION METHOD FOR COMPOSITION, AND PRODUCTION METHOD FOR UNSATURATED COMPOUND SHOWA DENKO KK (JP) 2023-03-01 EP disclosed
CN-112533895-B Composition, method for producing composition, and method for producing unsaturated compound 昭和电工株式会社 2023-02-17 CN disclosed
CN-114929668-A (meth) acrylate compound having isocyanate group and method for producing same 昭和电工株式会社 2022-08-19 CN disclosed
US-20220119585-A1 COMPOSITION, PRODUCTION METHOD FOR COMPOSITION, AND PRODUCTION METHOD FOR UNSATURATED COMPOUND SHOWA DENKO K.K. (JP) 2022-04-21 US disclosed
CN-102666618-A Metal-crosslinked organopolysiloxane thio-block vinyl copolymer and antifouling coating composition comprising same CHUGOKU MARINE PAINTS 2012-09-12 CN disclosed
US-20120205234-A1 POLYMERIZABLE MONOMER COMPOSITION AND METHOD FOR PREVENTING POLYMERIZATION SHOWA DENKO K.K. (JP) 2012-08-16 US disclosed
CN-101506252-B Thiourethane compound and photosensitive resin composition SHOWA DENKO KK 2011-06-15 CN disclosed
US-20110137066-A1 PROCESS OF INHIBITING POLYMERIZATION OF ISOCYANATE GROUP-CONTAINING, ETHYLENICALLY UNSATURATED CARBOXYLATE COMPOUNDS, AND PROCESS FOR PRODUCING THE COMPOUNDS SHOWA DENKO K.K. (JP) 2011-06-09 US disclosed
EP-2325166-A1 METHOD FOR INHIBITING POLYMERIZATION OF ETHYLENICALLY UNSATURATED CARBOXYLIC ACID ESTER COMPOUND CONTAINING ISOCYANATE GROUP AND METHOD FOR PRODUCING ETHYLENICALLY UNSATURATED CARBOXYLIC ACID ESTER COMPOUND CONTAINING ISOCYANATE GROUP Showa Denko K.K. (JP) 2011-05-25 EP disclosed
US-20100233596-A1 THIOURETHANE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION SHOWA DENKO K.K. (JP) 2010-09-16 US disclosed
US-20100099827-A1 POLYMERIZABLE MONOMER COMPOSITION AND METHOD FOR PREVENTING POLYMERIZATION SHOWA DENKO K.K. (JP) 2010-04-22 US disclosed
CN-101547955-A Polymerizable monomer composition and method for preventing polymerization SHOWA DENKO KK (JP) 2009-09-30 CN disclosed
CN-101506252-A Thiourethane compound and photosensitive resin composition SHOWA DENKO KK (JP) 2009-08-12 CN disclosed
EP-2055726-A1 THIOURETHANE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Showa Denko K.K. (JP) 2009-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11661474-B2 Composition, production method for composition, and production method for unsaturated compound ELOVL1, ACOX1, NCOA1 TSHR 3345/4885HPGD 775/4885
US-20110137066-A1 PROCESS OF INHIBITING POLYMERIZATION OF ISOCYANATE GROUP-CONTAINING, ETHYLENICALLY UNSATURATED CARBOXYLATE COMPOUNDS, AND PROCESS FOR PRODUCING THE COMPOUNDS ALKBH3, OGDH, IDH2 TSHR 4884/4885HPGD 244/4885
US-20100233596-A1 THIOURETHANE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION RCOR3, CBR3, TAS2R3 TSHR 3601/4885HPGD 834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.