Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18503370 | 0.95 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3HTR1ACHRNB2 | |
| SCHEMBL16962148 | 0.92 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3HTR1ACHRNB2 | |
| SCHEMBL13401946 | 0.91 | OPRL1 (0.46) | OPRL1 | |
| SCHEMBL10311700 | 0.89 | PDE2A (0.35) | SLC6A2SLC6A4SLC6A3HTR1ACHRNB2 | |
| SCHEMBL13408582 | 0.86 | DGAT1 (0.37) | SLC6A2SLC6A4SLC6A3OPRL1DRD4 | |
| SCHEMBL20103534 | 0.85 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3HTR1ACHRNB2 | |
| SCHEMBL13499926 | 0.85 | PTGDR2 (0.42) | SLC6A2SLC6A4SLC6A3HTR1ACHRNB2 | |
| SCHEMBL14864497 | 0.83 | PTGDR2 (0.44) | SLC6A2SLC6A4SLC6A3HTR1ACHRNB2 | |
| SCHEMBL15630469 | 0.81 | ESR2 (0.48) | OPRL1ESR2HTR2C | |
| SCHEMBL18499069 | 0.81 | ESR2 (0.48) | OPRL1ESR2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180201837-A1 | Method of Reducing ODF Mura in Polymer Stabilised Liquid Crystal Displays | MERCK PATENT GMBH (DE) | 2018-07-19 | — | — | US | disclosed |
| US-20170045765-A1 | LCD DEVICE | DIC CORPORATION (JP) | 2017-02-16 | — | — | US | disclosed |