Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12024476 | 0.92 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3HTR1ACHRNB2 | |
| SCHEMBL18503369 | 0.85 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3HTR1ACHRNB2 | |
| SCHEMBL13103961 | 0.85 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3HTR1ACHRNB2 | |
| SCHEMBL10206355 | 0.85 | PTGDR2 (0.45) | SLC6A2SLC6A4SLC6A3HTR1ACHRNB2 | |
| SCHEMBL765036 | 0.83 | PTGDR2 (0.48) | SLC6A2SLC6A4SLC6A3HTR1ACHRNB2 | |
| SCHEMBL18503370 | 0.81 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3HTR1ACHRNB2 | |
| SCHEMBL13993850 | 0.79 | APP (0.44) | SLC6A2SLC6A4SLC6A3HTR1ADRD4 | |
| SCHEMBL11096658 | 0.78 | TAS1R3 (0.45) | CHRNB2CHRNA4ESR2CA1CA2 | |
| SCHEMBL13401946 | 0.77 | OPRL1 (0.46) | — | |
| SCHEMBL16962148 | 0.76 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3HTR1ACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081047-A1 | CYCLOHEXYL GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |