Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18503392 | 0.93 | FFAR1 (0.41) | AAK1CYP3A4POLBAPEX1HTT | |
| SCHEMBL14984604 | 0.87 | POLB (0.40) | AAK1CYP3A4POLBAPEX1HTT | |
| SCHEMBL16140698 | 0.86 | THRB (0.44) | AAK1CYP3A4POLBAPEX1HTT | |
| SCHEMBL16559817 | 0.85 | THRB (0.37) | AAK1CYP3A4POLBAPEX1HTT | |
| SCHEMBL16436346 | 0.83 | ELANE (0.36) | CYP3A4POLBAPEX1HTTTDP1 | |
| SCHEMBL13289588 | 0.82 | MAOB (0.43) | POLBAPEX1HTTTDP1FFAR1 | |
| SCHEMBL16982209 | 0.81 | POLB (0.48) | AAK1CYP3A4POLBAPEX1HTT | |
| SCHEMBL21417794 | 0.81 | POLB (0.42) | AAK1CYP3A4POLBAPEX1HTT | |
| SCHEMBL9607788 | 0.81 | CFD (0.42) | AAK1CYP3A4HTTFFAR1ERN1 | |
| SCHEMBL16559842 | 0.80 | THRB (0.39) | AAK1CYP3A4POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170045765-A1 | LCD DEVICE | DIC CORPORATION (JP) | 2017-02-16 | — | — | US | disclosed |