⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231054 | 0.92 | — | — | |
| SCHEMBL951794 | 0.89 | ALDH1A1 (0.58) | — | |
| SCHEMBL7284851 | 0.89 | ALDH1A1 (0.58) | — | |
| SCHEMBL7282261 | 0.89 | ALDH1A1 (0.58) | — | |
| SCHEMBL7294711 | 0.89 | ALDH1A1 (0.58) | — | |
| SCHEMBL7290998 | 0.89 | ALDH1A1 (0.58) | — | |
| SCHEMBL2232193 | 0.89 | ALDH1A1 (0.58) | — | |
| SCHEMBL7285263 | 0.89 | ALDH1A1 (0.58) | — | |
| SCHEMBL196329 | 0.81 | — | — | |
| SCHEMBL4904158 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3921319-B1 | IMIDAZO [2, 1-F] [1, 2, 4] TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST | BEIGENE LTD (KY) | 2024-03-06 | — | — | EP | claimed |
| CN-111936496-B | Heterocyclic compounds useful as medicaments | 马萨里克大学 | 2023-12-29 | — | — | CN | claimed |
| US-20230167117-A1 | IMIDAZO[2,1-F][1,2,4]TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST | BEONE MEDICINES I GMBH (CH) | 2023-06-01 | — | — | US | claimed |
| US-11498920-B2 | 4-(1H-imidazol-5-yl)-1H-pyrrolo[2, 3-b] pyridines for use in the treatment of leukaemias, lymphomas and solid tumors | MASARYKOVA UNIVERZITA (CZ) | 2022-11-15 | — | — | US | claimed |
| EP-3774795-B1 | 4-(1H- IMIDAZOL- 5- YL) -1H-PYRROLO [2, 3-B] PYRIDINES FOR USE IN THE TREATMENT OF LEUKAEMIAS, LYMPHOMAS AND SOLID TUMORS | UNIV MASARYKOVA (CZ) | 2022-03-16 | — | — | EP | claimed |
| CN-113423708-A | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2021-09-21 | — | — | CN | claimed |
| EP-3774795-A1 | 4-(1H- IMIDAZOL- 5- YL) -1H-PYRROLO [2, 3-B] PYRIDINES FOR USE IN THE TREATMENT OF LEUKAEMIAS, LYMPHOMAS AND SOLID TUMORS | Masarykova Univerzita (CZ) | 2021-02-17 | — | — | EP | claimed |
| US-20210040086-A1 | 4-(1H- IMIDAZOL- 5- YL) -1H-PYRROLO [2, 3-B] PYRIDINES FOR USE IN THE TREATMENT OF LEUKAEMIAS, LYMPHOMAS AND SOLID TUMORS | MASARYKOVA UNIVERZITA (CZ) | 2021-02-11 | — | — | US | claimed |
| CN-111936496-A | Use of 4- (1H-imidazol-5-yl) -1H-pyrrolo [2,3-B ] pyridine for the treatment of leukemias, lymphomas and solid tumors | 马萨里克大学 | 2020-11-13 | — | — | CN | claimed |
| CN-111514123-A | Application of ketorolac analogue in resisting virus infection | 江苏伯克生物医药股份有限公司 | 2020-08-11 | — | — | CN | claimed |
| US-5545624-A | USEFUL IN TREATING BACTERIAL OR MYCOPLASMIC INFECTIONS | PFIZER INC. (US) | 1996-08-13 | — | — | US | claimed |
| EP-0708770-A1 | AMIDE DERIVATIVES OF 16-MEMBERED RING ANTIBIOTIC MACROLIDES | PFIZER (US) | 1996-05-01 | — | — | EP | claimed |
| EP-0705279-A1 | TOPOLOGICALLY SEGREGATED, ENCODED SOLID PHASE LIBRARIES | SELECTIDE CORPORATION (US) | 1996-04-10 | — | — | EP | claimed |
| WO-1996009312-A1 | ANTIBIOTIC MACROLIDES | PFIZER INC. (US) | 1996-03-28 | — | — | WO | claimed |
| EP-0649430-A1 | DERIVATIVES OF 16-MEMBERED RING ANTIBIOTIC MACROLIDES | PFIZER INC. (US) | 1995-04-26 | — | — | EP | claimed |
| WO-1995002594-A1 | AMIDE DERIVATIVES OF 16-MEMBERED RING ANTIBIOTIC MACROLIDES | PFIZER INC. (US) | 1995-01-26 | — | — | WO | claimed |
| WO-1994028028-A1 | TOPOLOGICALLY SEGREGATED, ENCODED SOLID PHASE LIBRARIES | SELECTIDE CORPORATION (US) | 1994-12-08 | — | — | WO | claimed |
| EP-0594540-A1 | Antiretroviral acyl compounds | CIBA-GEIGY AG (CH) | 1994-04-27 | — | — | EP | claimed |
| US-5302730-A | Acylation with acetic acid at positions one and seven; eliminating acyl group at position seven by solvolysis | NIPPON KAYAKU KK (JP) | 1994-04-12 | — | — | US | claimed |
| WO-1994002496-A1 | DERIVATIVES OF 16-MEMBERED RING ANTIBIOTIC MACROLIDES | PFIZER INC. (US) | 1994-02-03 | — | — | WO | claimed |