SCHEMBL951794

SCHEMBL951794

CN(C)CCCCCCCCCCC[C]=O

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.58
TSHR P16473 1/20 0.58
DNM1 Q05193 3/20 0.48
RAB9A P51151 1/20 0.39
SIGMAR1 Q99720 2/20 0.35
KDM4A O75164 11/20 0.35
KDM4C Q9H3R0 11/20 0.35
KDM5A P29375 1/20 0.35
KDM7A Q6ZMT4 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7284851 1.00 ALDH1A1 (0.58) ALDH1A1TSHRDNM1RAB9ASIGMAR1
SCHEMBL7282261 1.00 ALDH1A1 (0.58) ALDH1A1TSHRDNM1RAB9ASIGMAR1
SCHEMBL7294711 1.00 ALDH1A1 (0.58) ALDH1A1TSHRDNM1RAB9ASIGMAR1
SCHEMBL7285263 1.00 ALDH1A1 (0.58) ALDH1A1TSHRDNM1RAB9ASIGMAR1
SCHEMBL7290998 1.00 ALDH1A1 (0.58) ALDH1A1TSHRDNM1RAB9ASIGMAR1
SCHEMBL2232193 1.00 ALDH1A1 (0.58) ALDH1A1TSHRDNM1RAB9ASIGMAR1
SCHEMBL2231054 0.97
SCHEMBL1850341 0.89
SCHEMBL196329 0.77
SCHEMBL1676791 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9801850-B2 Antibacterial agent OSAKA UNIVERSITY (JP) 2017-10-31 US claimed
US-20150111961-A1 MEMBRANE FUSION INHIBITOR PROTECTEA, LTD. (JP) 2015-04-23 US claimed
EP-2460405-A1 ANTIBACTERIAL AGENT Osaka University (JP) 2012-06-06 EP claimed
US-20120136049-A1 ANTIBACTERIAL AGENT OSAKA UNIVERSITY (JP) 2012-05-31 US claimed
US-20110003889-A1 MEMBRANE FUSION INHIBITOR KAIHATSU, Kunihiro (JP) 2011-01-06 US claimed
US-9901565-B2 Membrane fusion inhibitor PROTECTEA, LTD. (JP) 2018-02-27 US disclosed
US-9801850-B2 Antibacterial agent OSAKA UNIVERSITY (JP) 2017-10-31 US disclosed
US-20150111961-A1 MEMBRANE FUSION INHIBITOR PROTECTEA, LTD. (JP) 2015-04-23 US disclosed
EP-2460405-B1 EPIGALLOCATECHIN GALLATE DERIVATIVE AS ANTIBACTERIAL AGENT UNIV OSAKA (JP) 2015-03-18 EP disclosed
US-8952055-B2 Membrane fusion inhibitor PROTECTEA, LTD. (JP) 2015-02-10 US disclosed
EP-2460405-A1 ANTIBACTERIAL AGENT Osaka University (JP) 2012-06-06 EP disclosed
US-20120136049-A1 ANTIBACTERIAL AGENT OSAKA UNIVERSITY (JP) 2012-05-31 US disclosed
US-20110003889-A1 MEMBRANE FUSION INHIBITOR KAIHATSU, Kunihiro (JP) 2011-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136049-A1 ANTIBACTERIAL AGENT TEAD4, ELOVL6, TEAD1 ALDH1A1 677/4885TSHR 2877/4885DNM1 812/4885
US-20150111961-A1 MEMBRANE FUSION INHIBITOR FLOT1, NSF, VAMP7 ALDH1A1 2332/4885TSHR 2134/4885DNM1 20/4885
US-20110003889-A1 MEMBRANE FUSION INHIBITOR FLOT1, NSF, VAMP7 ALDH1A1 2332/4885TSHR 2134/4885DNM1 20/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.