Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 9/20 | 0.51 |
| ▸ | PYGM | P11217 | 3/20 | 0.48 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.45 |
| ▸ | TK1 | P04183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL992386 | 1.00 | TK2 (0.51) | TK2PYGMDNPH1TK1 | |
| SCHEMBL20550056 | 1.00 | TK2 (0.51) | TK2PYGMDNPH1TK1 | |
| SCHEMBL18512963 | 1.00 | TK2 (0.51) | TK2PYGMDNPH1TK1 | |
| SCHEMBL992387 | 1.00 | TK2 (0.51) | TK2PYGMDNPH1TK1 | |
| SCHEMBL28948288 | 0.91 | TK2 (0.52) | TK2PYGMDNPH1 | |
| SCHEMBL28948294 | 0.91 | TK2 (0.52) | TK2PYGMDNPH1 | |
| SCHEMBL30865744 | 0.90 | TK2 (0.52) | TK2PYGMDNPH1TK1 | |
| SCHEMBL18573958 | 0.90 | TK2 (0.53) | TK2PYGMDNPH1 | |
| SCHEMBL17082399 | 0.90 | TK2 (0.53) | TK2PYGMDNPH1 | |
| SCHEMBL19614649 | 0.90 | TK2 (0.53) | TK2PYGMDNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044619-A1 | PROFILING CHEMICALLY MODIFIED DNA/RNA UNITS FOR DISEASE AND CANCER DIAGNOSIS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2017-02-16 | — | — | US | disclosed |