SCHEMBL992387

SCHEMBL992387

CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cc(CC(N)=O)c(=O)[nH]c1=O

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TK2 O00142 9/20 0.51
PYGM P11217 3/20 0.48
DNPH1 O43598 1/20 0.45
TK1 P04183 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL992386 1.00 TK2 (0.51) TK2PYGMDNPH1TK1
SCHEMBL20550056 1.00 TK2 (0.51) TK2PYGMDNPH1TK1
SCHEMBL18503556 1.00 TK2 (0.51) TK2PYGMDNPH1TK1
SCHEMBL18512963 1.00 TK2 (0.51) TK2PYGMDNPH1TK1
SCHEMBL28948288 0.91 TK2 (0.52) TK2PYGMDNPH1
SCHEMBL28948294 0.91 TK2 (0.52) TK2PYGMDNPH1
SCHEMBL30865744 0.90 TK2 (0.52) TK2PYGMDNPH1TK1
SCHEMBL18573958 0.90 TK2 (0.53) TK2PYGMDNPH1
SCHEMBL17082399 0.90 TK2 (0.53) TK2PYGMDNPH1
SCHEMBL19614649 0.90 TK2 (0.53) TK2PYGMDNPH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2875 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109727-A1 RNA CONSTRUCTS AND USES THEREOF BioNTech SE (DE) 2026-04-23 US claimed
US-20260078356-A1 COMPOSITIONS AND METHODS FOR TREATING ORNITHINE TRANSCARBAMYLASE DEFICIENCY ARCTURUS THERAPEUTICS INC (US) 2026-03-19 US claimed
EP-4705481-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2026-03-11 EP claimed
US-12503720-B2 Multiplexed profiling of RNA and DNA modifications Alida Biosciences Inc. (US) 2025-12-23 US claimed
EP-4634380-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-10-22 EP claimed
US-20250295744-A1 TREATMENT INVOLVING NON-IMMUNOGENIC RNA FOR ANTIGEN VACCINATION AND PD-1 AXIS BINDING ANTAGONISTS BioNTech SE (DE) 2025-09-25 US claimed
US-20250277223-A1 METHODS OF TREATING OR PREVENTING AUTOIMMUNE DISEASES IMCYSE SA (BE) 2025-09-04 US claimed
US-12398379-B2 Compositions and methods for treating ornithine transcarbamylase deficiency ARCTURUS THERAPEUTICS, INC. (US) 2025-08-26 US claimed
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 US claimed
EP-4598935-A2 RNA CONSTRUCTS AND USES THEREOF BioNTech SE (DE) 2025-08-13 EP claimed
WO-2018188730-A1 RNA FOR TREATMENT OF AUTOIMMUNE DISEASES BIONTECH RNA PHARMACEUTICALS GMBH (DE) 2018-10-18 WO claimed
US-9719084-B2 Co-transcriptional assembly of modified RNA nanoparticles THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2017-08-01 US claimed
US-9249473-B2 Compositions and methods for the identification of inhibitors of retroviral infection Trana Discover, Inc. (US) 2016-02-02 US claimed
US-20150203842-A1 CO-TRANSCRIPTIONAL ASSEMBLY OF MODIFIED RNA NANOPARTICLES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES 2015-07-23 US claimed
US-20140121124-A1 COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF RETROVIRAL INFECTION GUENTHER RICHARD H (US) 2014-05-01 US claimed
EP-2578685-A2 RNA containing modified nucleosides and methods of use thereof The Trustees of The University of Pennsylvania (US) 2013-04-10 EP claimed
EP-2201118-B1 COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF RETROVIRAL INFECTION TRANA DISCOVERY (US) 2012-04-18 EP claimed
US-20100291032-A1 COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF RETROVIRAL INFECTION TRANA DISCOVERY (US) 2010-11-18 US claimed
EP-2201118-A2 COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF RETROVIRAL INFECTION Trana Discovery (US) 2010-06-30 EP claimed
WO-2009036299-A2 COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF RETROVIRAL INFECTION TRANA DISCOVERY (US) 2009-03-19 WO claimed