Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 9/20 | 0.52 |
| ▸ | PYGM | P11217 | 3/20 | 0.47 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.44 |
| ▸ | TK1 | P04183 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18503556 | 0.90 | TK2 (0.51) | TK2PYGMDNPH1TK1 | |
| SCHEMBL992386 | 0.90 | TK2 (0.51) | TK2PYGMDNPH1TK1 | |
| SCHEMBL20550056 | 0.90 | TK2 (0.51) | TK2PYGMDNPH1TK1 | |
| SCHEMBL992387 | 0.90 | TK2 (0.51) | TK2PYGMDNPH1TK1 | |
| SCHEMBL18512963 | 0.90 | TK2 (0.51) | TK2PYGMDNPH1TK1 | |
| SCHEMBL30069461 | 0.89 | TK2 (0.53) | TK2PYGMDNPH1 | |
| SCHEMBL15810842 | 0.85 | PYGM (0.63) | TK2PYGMDNPH1TK1 | |
| SCHEMBL18870825 | 0.85 | PYGM (0.63) | TK2PYGMDNPH1TK1 | |
| SCHEMBL17082402 | 0.85 | PYGM (0.63) | TK2PYGMDNPH1TK1 | |
| SCHEMBL157978 | 0.85 | PYGM (0.63) | TK2PYGMDNPH1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565692-A2 | INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION | ModernaTX, Inc. (US) | 2025-06-11 | — | — | EP | claimed |
| WO-2024031087-A2 | INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION | MODERNATX, INC. (US) | 2024-02-08 | — | — | WO | claimed |
| EP-4565692-A2 | INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION | ModernaTX, Inc. (US) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024031087-A2 | INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION | MODERNATX, INC. (US) | 2024-02-08 | — | — | WO | disclosed |