Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | THPO | P40225 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18503533 | 0.84 | LMNA (0.41) | PNPLMNASMN1; SMN2ALDH1A1MTOR | |
| SCHEMBL18503534 | 0.73 | LMNA (0.43) | LMNASMN1; SMN2ALDH1A1MTORTHPO | |
| SCHEMBL17752033 | 0.72 | LMNA (0.42) | PNPLMNASMN1; SMN2ALDH1A1MTOR | |
| SCHEMBL15459909 | 0.72 | LMNA (0.42) | PNPLMNASMN1; SMN2ALDH1A1MTOR | |
| SCHEMBL25458669 | 0.69 | PYGM (0.44) | LMNAALDH1A1MTORTHPOPMP22 | |
| SCHEMBL25843063 | 0.69 | LMNA (0.38) | PNPLMNASMN1; SMN2ALDH1A1MTOR | |
| SCHEMBL17732549 | 0.69 | ADORA2A (0.41) | PNPLMNASMN1; SMN2ALDH1A1MTOR | |
| SCHEMBL27344654 | 0.68 | LMNA (0.38) | PNPLMNASMN1; SMN2ALDH1A1MTOR | |
| SCHEMBL26326168 | 0.68 | LMNA (0.38) | PNPLMNASMN1; SMN2ALDH1A1MTOR | |
| SCHEMBL288668 | 0.67 | LMNA (0.42) | LMNASMN1; SMN2ALDH1A1MTORTHPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044619-A1 | PROFILING CHEMICALLY MODIFIED DNA/RNA UNITS FOR DISEASE AND CANCER DIAGNOSIS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2017-02-16 | — | — | US | disclosed |