Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FNIP1 | Q8TF40 | 1/20 | 0.31 |
| ▸ | FEM1B | Q9UK73 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1849845 | 0.93 | GPR52 (0.44) | GPR52ALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL1855790 | 0.90 | GPR52 (0.45) | GPR52ALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL3218910 | 0.83 | GPR52 (0.58) | GPR52EIF4EBP1 | |
| SCHEMBL1849555 | 0.81 | GPR52 (0.51) | GPR52ALDH1A1RAB9ARXFP1NPC1 | |
| SCHEMBL1852443 | 0.81 | GPR52 (0.52) | GPR52RAB9AEIF4EBP1NPC1L3MBTL1 | |
| SCHEMBL1846596 | 0.81 | GPR52 (0.53) | GPR52ALDH1A1 | |
| SCHEMBL1850387 | 0.80 | GPR52 (0.55) | GPR52EIF4EBP1 | |
| SCHEMBL3208407 | 0.76 | GPR52 (0.49) | GPR52ALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL1850974 | 0.75 | GPR52 (0.44) | GPR52RXFP1 | |
| SCHEMBL1852679 | 0.75 | GPR52 (0.72) | GPR52HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |