SCHEMBL18504290

SCHEMBL18504290

CCCOC(=O)c1cccc(I)c1COc1ccn(O)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
TSHR P16473 5/20 0.36
TDP1 Q9NUW8 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
CYP3A4 P08684 2/20 0.36
MAPK1 P28482 2/20 0.36
TP53 P04637 1/20 0.36
LMNA P02545 2/20 0.35
JMJD6 Q6NYC1 1/20 0.35
ESR1 P03372 1/20 0.34
CHRM1 P11229 1/20 0.34
SLC6A2 P23975 1/20 0.34
KDR P35968 1/20 0.34
ELANE P08246 2/20 0.34
PDK2 Q15119 1/20 0.34
PRTN3 P24158 1/20 0.34
HSD17B10 Q99714 2/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18504960 0.91 TSHR (0.41) ALDH1A1TSHRTDP1L3MBTL1TP53
SCHEMBL18504667 0.88 ALDH1A1 (0.45) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL18504288 0.88 ALDH1A1 (0.45) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL18504967 0.87 ALDH1A1 (0.44) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL18504289 0.87 ALDH1A1 (0.44) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL18504404 0.87 ALDH1A1 (0.44) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL18504421 0.87 ALDH1A1 (0.44) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL18504598 0.86 POLB (0.38) ALDH1A1TSHRTDP1TP53LMNA
SCHEMBL18504685 0.86 ALDH1A1 (0.43) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL18504401 0.86 ALDH1A1 (0.43) ALDH1A1TSHRTDP1L3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9565856-B2 Tetrazolinone compounds and its use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-14 US disclosed