Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18504960 | 0.88 | TSHR (0.41) | POLBTP53TDP1KDM4EKMT2A | |
| SCHEMBL18504390 | 0.87 | NPC1 (0.36) | POLBKDM4ELMNAKMT2AALDH1A1 | |
| SCHEMBL18500066 | 0.87 | ALDH1A1 (0.40) | POLBTP53TDP1KDM4ELMNA | |
| SCHEMBL18504945 | 0.86 | NR1H4 (0.35) | TDP1KDM4EKMT2AALDH1A1 | |
| SCHEMBL18504290 | 0.86 | ALDH1A1 (0.44) | TP53TDP1KDM4ELMNAALDH1A1 | |
| SCHEMBL18504220 | 0.86 | KMT2A (0.40) | POLBTP53TDP1KDM4ELMNA | |
| SCHEMBL18504649 | 0.86 | TDP1 (0.41) | POLBTP53TDP1KDM4EKMT2A | |
| SCHEMBL18504188 | 0.86 | MAPT (0.40) | POLBTP53TDP1KDM4ELMNA | |
| SCHEMBL18504646 | 0.86 | PDE5A (0.35) | KDM4ESMN1; SMN2 | |
| SCHEMBL18504768 | 0.86 | NR1H4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |