SCHEMBL18504293

SCHEMBL18504293

CC(C)OC(=O)c1cccc(Cl)c1COc1ccn(O)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
NPC1 O15118 1/20 0.36
TDP1 Q9NUW8 2/20 0.35
USP2 O75604 1/20 0.35
KMT2A Q03164 2/20 0.35
SGMS2 Q8NHU3 1/20 0.35
ALDH1A1 P00352 1/20 0.35
ATM Q13315 1/20 0.35
TP53 P04637 1/20 0.34
GABRA5 P31644 1/20 0.34
ADORA1 P30542 1/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22564237 0.88 NR1H4 (0.39) NR1H4L3MBTL1KDM4EPOLBMAPT
SCHEMBL18504678 0.88 GABRA5 (0.37) NR1H4L3MBTL1KDM4EPOLBMAPT
SCHEMBL18504649 0.87 TDP1 (0.41) NR1H4KDM4EPOLBNPSR1NPC1
SCHEMBL18504968 0.87 MAPT (0.38) L3MBTL1KDM4EPOLBMAPTNPSR1
SCHEMBL18504648 0.87 NPC1 (0.36) NR1H4L3MBTL1KDM4EPOLBMAPT
SCHEMBL18504390 0.87 NPC1 (0.36) NR1H4L3MBTL1KDM4EPOLBMAPT
SCHEMBL18504297 0.87 NPC1 (0.36) NR1H4L3MBTL1KDM4EPOLBMAPT
SCHEMBL18504972 0.87 NPC1 (0.36) NR1H4L3MBTL1KDM4EPOLBMAPT
SCHEMBL18504942 0.86 NPC1 (0.34) NR1H4L3MBTL1KDM4EPOLBMAPT
SCHEMBL18504693 0.86 IRAK4 (0.36) NR1H4L3MBTL1KDM4EPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9565856-B2 Tetrazolinone compounds and its use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-14 US disclosed