Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18500715 | 0.89 | HSD17B10 (0.41) | TSHRL3MBTL1TDP1POLBHSD17B10 | |
| SCHEMBL18504653 | 0.89 | ALDH1A1 (0.46) | TSHRL3MBTL1TDP1POLBHSD17B10 | |
| SCHEMBL18500326 | 0.88 | NR1H4 (0.36) | TSHRL3MBTL1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL18504957 | 0.88 | POLB (0.40) | TSHRL3MBTL1TDP1POLBHSD17B10 | |
| SCHEMBL18504969 | 0.88 | NPC1 (0.34) | L3MBTL1POLBRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL22564207 | 0.88 | TSHR (0.42) | TSHRL3MBTL1TDP1POLBHSD17B10 | |
| SCHEMBL18504862 | 0.88 | TSHR (0.34) | TSHRL3MBTL1TDP1HSD17B10RAB9A | |
| SCHEMBL18504748 | 0.87 | NPC1 (0.33) | TSHRL3MBTL1TDP1HSD17B10RAB9A | |
| SCHEMBL18504782 | 0.87 | TSHR (0.32) | TSHRL3MBTL1TDP1HSD17B10RAB9A | |
| SCHEMBL18504521 | 0.87 | L3MBTL1 (0.32) | TSHRL3MBTL1TDP1HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |