Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.62 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.59 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | KDM4A | O75164 | 2/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3221864 | 0.87 | GPR52 (0.75) | KDM4CGPR52PTGER4NR4A2MRGPRX4 | |
| SCHEMBL7961131 | 0.87 | GPR52 (0.80) | KDM4CGPR52PTGER4MRGPRX4 | |
| SCHEMBL3219255 | 0.84 | GPR52 (0.66) | KDM4CGPR52PTGER4POLB | |
| SCHEMBL1854239 | 0.84 | GPR52 (0.63) | KDM4CGPR52PTGER4MRGPRX4MMP13 | |
| SCHEMBL1849426 | 0.83 | GPR52 (0.46) | KDM4CGPR52PTGER4NR4A2KDM4A | |
| SCHEMBL1850158 | 0.83 | GPR52 (0.56) | KDM4CGPR52PTGER4POLB | |
| SCHEMBL1853421 | 0.81 | GPR52 (0.64) | KDM4CGPR52PTGER4NR4A2MMP13 | |
| SCHEMBL13505964 | 0.80 | GPR52 (0.53) | KDM4CGPR52PTGER4POLB | |
| SCHEMBL1849610 | 0.79 | GPR52 (0.93) | KDM4CGPR52PTGER4MRGPRX4 | |
| SCHEMBL1850188 | 0.79 | GPR52 (0.59) | KDM4CGPR52PTGER4MMP13KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |
| US-20100041891-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041891-A1 | AMIDE COMPOUND | GPR52, GPR132, NR5A2 | KDM4C 2640/4885GPR52 1/4885PTGER4 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.