Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18504704 | 0.90 | NR1H4 (0.37) | NR1H4ALDH1A1TDP1AKR1B1SGMS2 | |
| SCHEMBL18504724 | 0.89 | NR1H4 (0.39) | NR1H4ALDH1A1TDP1SGMS2SMN1; SMN2 | |
| SCHEMBL18504705 | 0.89 | PARP1 (0.38) | NR1H4ALDH1A1TDP1SGMS2SMN1; SMN2 | |
| SCHEMBL18505005 | 0.86 | SGMS2 (0.39) | NR1H4HTTALDH1A1TDP1SGMS2 | |
| SCHEMBL18504406 | 0.86 | SGMS2 (0.39) | NR1H4HTTALDH1A1TDP1SGMS2 | |
| SCHEMBL18504649 | 0.86 | TDP1 (0.41) | NR1H4TP53HTTALDH1A1TDP1 | |
| SCHEMBL18504787 | 0.86 | HDAC3 (0.41) | NR1H4HTTALDH1A1TDP1SGMS2 | |
| SCHEMBL18504671 | 0.86 | SMN1; SMN2 (0.46) | NR1H4ALDH1A1SMN1; SMN2 | |
| SCHEMBL22564462 | 0.86 | NR1H4 (0.42) | NR1H4TP53HTTTSHRALDH1A1 | |
| SCHEMBL18504945 | 0.85 | NR1H4 (0.35) | NR1H4ALDH1A1TDP1ALKBH1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |