Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18505005 | 0.91 | SGMS2 (0.39) | HDAC3HDAC1HDAC2HDAC6SGMS2 | |
| SCHEMBL18504406 | 0.91 | SGMS2 (0.39) | HDAC3HDAC1HDAC2HDAC6SGMS2 | |
| SCHEMBL22564176 | 0.87 | HDAC3 (0.41) | HDAC3HDAC1HDAC2HDAC6SGMS2 | |
| SCHEMBL18504583 | 0.87 | ALDH1A1 (0.33) | TDP1PDE5AKDM4EALDH1A1KMT2A | |
| SCHEMBL18504615 | 0.86 | NR1H4 (0.43) | SGMS2NR1H4TDP1ALDH1A1HTT | |
| SCHEMBL18504704 | 0.86 | NR1H4 (0.37) | SGMS2NR1H4ITGB1ITGA4TDP1 | |
| SCHEMBL18504821 | 0.86 | HDAC3 (0.41) | HDAC3HDAC1HDAC2HDAC6SGMS2 | |
| SCHEMBL18504649 | 0.86 | TDP1 (0.41) | NR1H4TDP1POLBKDM4EALDH1A1 | |
| SCHEMBL18504646 | 0.86 | PDE5A (0.35) | HDAC3HDAC1HDAC2HDAC6PDE5A | |
| SCHEMBL18504865 | 0.86 | HDAC1 (0.36) | HDAC1HDAC6SGMS2TDP1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |