Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18504301 | 0.88 | GRIN1 (0.35) | NR1H4SMN1; SMN2PKMP2RX7HSD11B1 | |
| SCHEMBL18504690 | 0.86 | SMN1; SMN2 (0.38) | SMN1; SMN2PKMMC4RLMNAMAPT | |
| SCHEMBL18504471 | 0.85 | MEN1 (0.31) | NR1H4 | |
| SCHEMBL18504714 | 0.85 | NISCH (0.33) | NR1H4 | |
| SCHEMBL18504347 | 0.85 | MCHR1 (0.35) | NR1H4 | |
| SCHEMBL22564313 | 0.85 | NR1H4 (0.36) | NR1H4SMN1; SMN2PKMMC4RP2RX7 | |
| SCHEMBL18504563 | 0.85 | ALDH1A1 (0.37) | NR1H4SMN1; SMN2PKMLMNAMAPT | |
| SCHEMBL18504671 | 0.84 | SMN1; SMN2 (0.46) | NR1H4SMN1; SMN2PKMKDM4ELMNA | |
| SCHEMBL18504496 | 0.84 | IRAK4 (0.36) | NR1H4KDM4ELMNA | |
| SCHEMBL18500065 | 0.83 | BRPF1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |