SCHEMBL18504752

SCHEMBL18504752

O=C(Br)c1cccc(CF)c1COc1ccn(O)n1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 1/20 0.31
FOLH1 Q04609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18504157 0.89 NR1H4 (0.35) NR1H4FOLH1
SCHEMBL18504509 0.89 NR1H4 (0.33) NR1H4FOLH1
SCHEMBL18504769 0.88 MEN1 (0.36)
SCHEMBL18504338 0.88 NR1H4 (0.31) NR1H4
SCHEMBL18504398 0.87 LTB4R (0.33) NR1H4
SCHEMBL22563884 0.87 FOLH1 (0.32) NR1H4FOLH1
SCHEMBL18500404 0.86 ALDH1A1 (0.35)
SCHEMBL18504779 0.86 PDE5A (0.32)
SCHEMBL18504735 0.85 TDP1 (0.36) NR1H4
SCHEMBL18505004 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9565856-B2 Tetrazolinone compounds and its use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-14 US disclosed