SCHEMBL18504763

SCHEMBL18504763

O=C(Br)c1cccc(OC(F)(F)F)c1COc1ccn(O)n1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
SCN9A Q15858 3/20 0.33
KCNK3 O14649 3/20 0.32
KCNK9 Q9NPC2 3/20 0.32
HCRTR1 O43613 5/20 0.32
HCRTR2 O43614 5/20 0.32
SCN10A Q9Y5Y9 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
F2R P25116 1/20 0.31
GUCY1B2 O75343 1/20 0.31
GUCY1A2 P33402 1/20 0.31
GUCY1A1 Q02108 1/20 0.31
GUCY1B1 Q02153 1/20 0.31
FFAR1 O14842 1/20 0.31
NR1H4 Q96RI1 1/20 0.31
SSTR4 P31391 1/20 0.31
PRKAG1 P54619 1/20 0.31
PRKAA2 P54646 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18504652 0.90 RXRA (0.39) RXRARXRBRXRGSCN9AKCNK3
SCHEMBL18504989 0.89 RXRA (0.34) RXRARXRBRXRGSCN9AKCNK3
SCHEMBL18504727 0.89 SCN9A (0.41) RXRARXRBRXRGSCN9ASCN10A
SCHEMBL22564516 0.88 RXRA (0.36) RXRARXRBRXRGSCN9AKCNK3
SCHEMBL18504661 0.87 HDAC1 (0.40) RXRARXRBRXRGSCN9AKCNK3
SCHEMBL18504239 0.87 KCNK3 (0.37) KCNK3KCNK9HCRTR1HCRTR2F2R
SCHEMBL18504717 0.86 NR1H4 (0.30) NR1H4
SCHEMBL18504801 0.86 KCNK3 (0.35) RXRARXRBRXRGSCN9AKCNK3
SCHEMBL18504672 0.85 SCN9A (0.41) SCN9AHCRTR1HCRTR2MRGPRX4
SCHEMBL18504747 0.85 NPC1 (0.36) SCN9AMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9565856-B2 Tetrazolinone compounds and its use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-14 US disclosed