Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.31 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | GUCY1B2 | O75343 | 3/20 | 0.31 |
| ▸ | GUCY1A2 | P33402 | 3/20 | 0.31 |
| ▸ | GUCY1A1 | Q02108 | 3/20 | 0.31 |
| ▸ | GUCY1B1 | Q02153 | 3/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | F2R | P25116 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22563835 | 0.90 | RXRA (0.39) | RXRARXRBRXRGHCRTR1HCRTR2 | |
| SCHEMBL22563947 | 0.89 | KCNK3 (0.34) | RXRARXRBRXRGSCN9AKCNK3 | |
| SCHEMBL22564383 | 0.89 | SCN9A (0.38) | RXRARXRBRXRGSCN9ASCN10A | |
| SCHEMBL22564344 | 0.89 | RXRA (0.33) | RXRARXRBRXRGHCRTR1HCRTR2 | |
| SCHEMBL18504763 | 0.88 | RXRA (0.36) | RXRARXRBRXRGHCRTR1HCRTR2 | |
| SCHEMBL22564482 | 0.87 | KCNK3 (0.36) | HCRTR1HCRTR2KCNK3KCNK9F2R | |
| SCHEMBL22564308 | 0.87 | HDAC6 (0.39) | RXRARXRBRXRGSCN9AKCNK3 | |
| SCHEMBL22564365 | 0.87 | NR1H4 (0.30) | NR1H4 | |
| SCHEMBL22564291 | 0.86 | KCNK3 (0.35) | RXRARXRBRXRGSCN9AKCNK3 | |
| SCHEMBL22564307 | 0.85 | NPC1 (0.36) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |