Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18504464 | 0.91 | NR1H4 (0.35) | NR1H4KCNK3KCNK9GABRA1GABRG2 | |
| SCHEMBL18504785 | 0.90 | NR1H4 (0.36) | NR1H4KCNK3KCNK9GABRA1GABRG2 | |
| SCHEMBL18504998 | 0.89 | NR1H4 (0.37) | NR1H4GABRA1GABRG2GABRB3NLRP3 | |
| SCHEMBL22564126 | 0.88 | NR1H4 (0.36) | NR1H4KCNK3KCNK9GABRA1GABRG2 | |
| SCHEMBL18504645 | 0.88 | KDM4E (0.39) | NR1H4KCNK3KCNK9GABRA1GABRG2 | |
| SCHEMBL18500393 | 0.87 | NR1H4 (0.41) | NR1H4GABRA1GABRG2GABRB3 | |
| SCHEMBL18504708 | 0.86 | NR1H4 (0.37) | NR1H4GABRA1GABRG2GABRB3NLRP3 | |
| SCHEMBL18504533 | 0.86 | NR1H4 (0.35) | NR1H4GABRA1GABRG2GABRB3KMT2A | |
| SCHEMBL18504567 | 0.85 | SGMS2 (0.39) | NR1H4KMT2ASMN1; SMN2 | |
| SCHEMBL18504297 | 0.84 | NPC1 (0.36) | NR1H4GABRA1GABRG2GABRB3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |