SCHEMBL18504780

SCHEMBL18504780

C#Cc1cccc(C(=O)NCl)c1COc1ccn(O)n1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 2/20 0.31
SGMS2 Q8NHU3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18504832 0.90 PDE5A (0.31)
SCHEMBL22563972 0.88 NR1H4 (0.31) NR1H4SGMS2
SCHEMBL18504457 0.88 NR1H4 (0.32) NR1H4
SCHEMBL18504601 0.87 NR1H4 (0.30) NR1H4
SCHEMBL18504925 0.86 NR1H4 (0.36) NR1H4
SCHEMBL18505005 0.86 SGMS2 (0.39) NR1H4SGMS2
SCHEMBL18504383 0.86 KDM4E (0.34)
SCHEMBL18504346 0.85 NR1H4 (0.32) NR1H4
SCHEMBL18504781 0.85 PARP1 (0.35) NR1H4
SCHEMBL18504789 0.83 SGMS2 (0.38) NR1H4SGMS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9565856-B2 Tetrazolinone compounds and its use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-14 US disclosed