Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | LIG1 | P18858 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18504780 | 0.90 | NR1H4 (0.31) | — | |
| SCHEMBL22564102 | 0.88 | PDE5A (0.31) | PDE5ALIG1 | |
| SCHEMBL18504925 | 0.87 | NR1H4 (0.36) | — | |
| SCHEMBL18504627 | 0.87 | ADAM17 (0.32) | PDE5ALIG1 | |
| SCHEMBL18504383 | 0.87 | KDM4E (0.34) | — | |
| SCHEMBL18504457 | 0.86 | NR1H4 (0.32) | — | |
| SCHEMBL18504346 | 0.86 | NR1H4 (0.32) | — | |
| SCHEMBL18504781 | 0.86 | PARP1 (0.35) | HDAC8HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL18504787 | 0.85 | HDAC3 (0.41) | PDE5AHDAC8HDAC3HDAC1HDAC2 | |
| SCHEMBL18504942 | 0.84 | NPC1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9565856-B2 | Tetrazolinone compounds and its use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-02-14 | — | — | US | disclosed |