Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18504939 | 0.87 | SMN1; SMN2 (0.33) | SMN1; SMN2PKMHTTHSD17B10LMNA | |
| SCHEMBL16307270 | 0.85 | FDPS (0.34) | SMN1; SMN2PKMHTTHSD17B10MEN1 | |
| SCHEMBL14716584 | 0.83 | SMN1; SMN2 (0.35) | SMN1; SMN2PKMHTTHSD17B10LMNA | |
| SCHEMBL16307272 | 0.78 | ACE2 (0.36) | SMN1; SMN2PKMHTTHSD17B10SHMT2 | |
| SCHEMBL16307283 | 0.76 | LMNA (0.35) | SMN1; SMN2PKMHTTHSD17B10LMNA | |
| SCHEMBL16604934 | 0.76 | LMNA (0.35) | SMN1; SMN2PKMHTTHSD17B10LMNA | |
| SCHEMBL16604924 | 0.75 | LMNA (0.34) | SMN1; SMN2PKMHTTHSD17B10LMNA | |
| SCHEMBL18517127 | 0.74 | SMN1; SMN2 (0.38) | SMN1; SMN2PKMHTTHSD17B10LMNA | |
| SCHEMBL14881262 | 0.74 | SMN1; SMN2 (0.38) | SMN1; SMN2PKMHTTHSD17B10LMNA | |
| SCHEMBL12748824 | 0.74 | SMN1; SMN2 (0.35) | SMN1; SMN2PKMHTTHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044309-A1 | PREPARATION OF HIGH MOLECULAR WEIGHT POLYMERS BY DIRECT ARYLATION AND HETEROARYLATION | UNIVERSITE LAVAL (CA) | 2017-02-16 | — | — | US | disclosed |