Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.36 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | SLC34A1 | Q06495 | 3/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24045230 | 0.88 | PDE10A (0.35) | PDE10ADDR1SLC34A1EGLN1 | |
| SCHEMBL18506150 | 0.86 | POLB (0.43) | PDE10ADDR1SLC34A1EGLN1POLB | |
| SCHEMBL18506069 | 0.83 | AGPAT2 (0.41) | PDE10ADDR1AGPAT2CNR2GRM2 | |
| SCHEMBL18498843 | 0.82 | PDE10A (0.38) | PDE10ADDR1AGPAT2EGLN1KIT | |
| SCHEMBL18506070 | 0.82 | AGPAT2 (0.39) | PDE10ADDR1AGPAT2CNR2GRM2 | |
| SCHEMBL23934171 | 0.81 | PDE10A (0.38) | PDE10AAGPAT2CNR2SLC34A1GRM2 | |
| SCHEMBL18357970 | 0.81 | DDR1 (0.34) | PDE10ADDR1SLC34A1EGLN1 | |
| SCHEMBL14678088 | 0.79 | POLB (0.40) | PDE10ADDR1AGPAT2CNR2GRM2 | |
| SCHEMBL14677508 | 0.78 | HTR2B (0.39) | PDE10ADDR1AGPAT2CNR2GRM2 | |
| SCHEMBL9280305 | 0.77 | AGPAT2 (0.38) | PDE10ADDR1AGPAT2CNR2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331870-B1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-06-16 | — | — | EP | disclosed |
| WO-2017025419-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | WO | disclosed |