Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22349480 | 0.91 | CYP3A4 (0.32) | EGLN1 | |
| SCHEMBL18357972 | 0.84 | DDR1 (0.35) | DDR1PDE10AEGLN1SLC34A1 | |
| SCHEMBL17494910 | 0.84 | DDR1 (0.32) | DDR1EGLN1 | |
| SCHEMBL22291717 | 0.81 | DDR1 (0.32) | DDR1MAOB | |
| SCHEMBL18506068 | 0.81 | PDE10A (0.39) | DDR1PDE10AEGLN1SLC34A1 | |
| SCHEMBL18506150 | 0.80 | POLB (0.43) | DDR1PDE10AEGLN1SLC34A1 | |
| SCHEMBL24045230 | 0.79 | PDE10A (0.35) | DDR1PDE10AEGLN1SLC34A1 | |
| SCHEMBL18357996 | 0.78 | LMNA (0.36) | DDR1MAOB | |
| SCHEMBL23811190 | 0.77 | DDR1 (0.30) | DDR1 | |
| SCHEMBL22779591 | 0.77 | PDE10A (0.32) | DDR1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3317276-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-16 | — | — | EP | disclosed |
| US-10745396-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-18 | — | — | US | disclosed |
| WO-2017001314-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745396-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | DDT, SQOR, ACHE | DDR1 4468/4885PDE10A 1200/4885EGLN1 3453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.