SCHEMBL18506328 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	CPS1	P31327	15/20	0.53

▸	HPGD	P15428	3/20	0.43

▸	MEN1	O00255	2/20	0.43

▸	LMNA	P02545	2/20	0.43

▸	KMT2A	Q03164	2/20	0.43

▸	ALDH1A1	P00352	2/20	0.43

▸	GAA	P10253	1/20	0.43

▸	ALOX12	P18054	1/20	0.43

▸	NPC1	O15118	1/20	0.42

▸	RAB9A	P51151	1/20	0.42

▸	CYP3A4	P08684	1/20	0.41

▸	MAPK1	P28482	1/20	0.41

▸	CYP1A1	P04798	1/20	0.40

▸	CYP1A2	P05177	1/20	0.40

▸	CYP1B1	Q16678	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL531476	0.83	CPS1 (0.54)	CPS1HPGDMEN1LMNAKMT2A
SCHEMBL30820833	0.83	CPS1 (0.54)	CPS1HPGDMEN1LMNAKMT2A
SCHEMBL10086344	0.83	CPS1 (0.54)	CPS1HPGDMEN1LMNAKMT2A
SCHEMBL1555099	0.81	CPS1 (0.61)	CPS1HPGDMEN1LMNAKMT2A
SCHEMBL13470770	0.79	MAPT (0.58)	HPGDMEN1LMNAKMT2AALDH1A1
SCHEMBL18489238	0.79	CPS1 (0.50)	CPS1HPGDMEN1LMNAKMT2A
SCHEMBL18502969	0.79	CPS1 (0.50)	CPS1HPGDMEN1LMNAKMT2A
SCHEMBL18489241	0.79	CPS1 (0.50)	CPS1HPGDMEN1LMNAKMT2A
SCHEMBL28102429	0.79	CPS1 (0.57)	CPS1HPGDMEN1LMNAKMT2A
SCHEMBL15226106	0.78	CPS1 (0.61)	CPS1HPGDMEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2017027600-A1	GEMINAL SUBSTITUTED AMINOBENZISOXAZOLE COMPOUNDS AS AGONISTS OF α7-NICOTINIC ACETYLCHOLINE RECEPTORS	FORUM PHARMACEUTICALS, INC. (US)	2017-02-16	—	—	WO	disclosed