Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 11/20 | 0.75 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3212221 | 0.89 | GPR52 (0.76) | GPR52S1PR5S1PR4AURKASNCA | |
| SCHEMBL3205301 | 0.88 | GPR52 (0.79) | GPR52S1PR5S1PR4AURKASNCA | |
| SCHEMBL3235324 | 0.87 | GPR52 (0.78) | GPR52S1PR5S1PR4AURKASNCA | |
| SCHEMBL29452903 | 0.86 | GPR52 (1.00) | GPR52SNCA | |
| SCHEMBL3204244 | 0.86 | GPR52 (0.71) | GPR52S1PR5S1PR4 | |
| SCHEMBL3196505 | 0.86 | GPR52 (0.76) | GPR52S1PR5S1PR4AURKASNCA | |
| SCHEMBL3197888 | 0.86 | GPR52 (0.81) | GPR52 | |
| SCHEMBL3198777 | 0.86 | GPR52 (1.00) | GPR52SNCA | |
| SCHEMBL13489634 | 0.85 | GPR52 (0.78) | GPR52S1PR5S1PR4SNCA | |
| SCHEMBL1851733 | 0.85 | GPR52 (0.76) | GPR52S1PR5S1PR4AURKASNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |