Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 9/20 | 0.69 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3206485 | 0.87 | GPR52 (0.73) | GPR52S1PR5S1PR4 | |
| SCHEMBL3206767 | 0.86 | GPR52 (0.70) | GPR52S1PR5S1PR4UTS2R | |
| SCHEMBL3201286 | 0.86 | GPR52 (0.70) | GPR52S1PR5S1PR4UTS2R | |
| SCHEMBL3212221 | 0.85 | GPR52 (0.76) | GPR52S1PR5S1PR4 | |
| SCHEMBL3204244 | 0.85 | GPR52 (0.71) | GPR52S1PR5S1PR4 | |
| SCHEMBL3235324 | 0.85 | GPR52 (0.78) | GPR52S1PR5S1PR4 | |
| SCHEMBL1850697 | 0.84 | GPR52 (0.75) | GPR52S1PR5S1PR4 | |
| SCHEMBL3205301 | 0.84 | GPR52 (0.79) | GPR52S1PR5S1PR4 | |
| SCHEMBL3196505 | 0.83 | GPR52 (0.76) | GPR52S1PR5S1PR4 | |
| SCHEMBL1849572 | 0.82 | GPR52 (0.71) | GPR52S1PR5S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |