Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 3/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 6/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209831 | 0.97 | ROCK1 (0.43) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| SCHEMBL1849782 | 0.96 | KDM4C (0.43) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| SCHEMBL1856110 | 0.94 | KDM4C (0.51) | KDM4CNR4A2ROCK1SCDGPR52 | |
| SCHEMBL1853064 | 0.91 | KDM4C (0.48) | KDM4CNR4A2ROCK1GPR52MRGPRX4 | |
| SCHEMBL3217369 | 0.87 | GPR52 (0.50) | KDM4CROCK1GPR52 | |
| SCHEMBL1856629 | 0.84 | GPR52 (0.56) | GPR52 | |
| SCHEMBL1851239 | 0.84 | GPR52 (0.57) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| SCHEMBL1850602 | 0.82 | GPR52 (0.49) | NR4A2GPR52MRGPRX4LIPGPTGER4 | |
| SCHEMBL1852205 | 0.82 | GPR52 (0.47) | KDM4ENR4A2GPR52MRGPRX4LMNA | |
| SCHEMBL3210823 | 0.80 | GPR52 (0.61) | SCDGPR52MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |