Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | GPR52 | Q9Y2T5 | 10/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3217369 | 0.97 | GPR52 (0.50) | KDM4CGPR52ROCK1AURKARPS6KB1 | |
| SCHEMBL1856110 | 0.97 | KDM4C (0.51) | KDM4CGPR52NR4A2ROCK1MRGPRX4 | |
| SCHEMBL1850776 | 0.91 | KDM4C (0.46) | KDM4CGPR52NR4A2ROCK1MRGPRX4 | |
| SCHEMBL1849782 | 0.88 | KDM4C (0.43) | KDM4CGPR52NR4A2ROCK1MRGPRX4 | |
| SCHEMBL3209831 | 0.87 | ROCK1 (0.43) | KDM4CGPR52ROCK1MRGPRX4 | |
| SCHEMBL1856629 | 0.84 | GPR52 (0.56) | GPR52 | |
| SCHEMBL1850602 | 0.84 | GPR52 (0.49) | GPR52NR4A2MRGPRX4LIPG | |
| SCHEMBL1852235 | 0.84 | GPR52 (0.54) | GPR52MAOB | |
| SCHEMBL1849882 | 0.83 | GPR52 (0.57) | KDM4CGPR52NR4A2 | |
| SCHEMBL1852456 | 0.80 | GPR52 (0.46) | GPR52MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |