Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 4/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1856086 | 0.89 | MEN1 (0.42) | MRGPRX4NR4A2GPR52MAOB | |
| SCHEMBL1850062 | 0.88 | MRGPRX4 (0.57) | MRGPRX4NR4A2PPARGMCL1S1PR4 | |
| SCHEMBL1851849 | 0.86 | GPR52 (0.59) | MRGPRX4NR4A2S1PR4S1PR5GPR52 | |
| SCHEMBL3219557 | 0.86 | GPR52 (0.61) | MRGPRX4GPR52 | |
| SCHEMBL1852635 | 0.85 | GPR52 (0.57) | MRGPRX4NR4A2KDM4CS1PR4S1PR5 | |
| SCHEMBL1850131 | 0.81 | MRGPRX4 (0.49) | MRGPRX4NR4A2PPARGMCL1S1PR4 | |
| SCHEMBL1849882 | 0.81 | GPR52 (0.57) | NR4A2KDM4CS1PR4S1PR5GPR52 | |
| SCHEMBL1851239 | 0.81 | GPR52 (0.57) | NR4A2KDM4CGPR52 | |
| SCHEMBL1850678 | 0.79 | GPR52 (0.56) | MRGPRX4NR4A2MCL1S1PR4S1PR5 | |
| SCHEMBL1850224 | 0.79 | KDM4C (0.48) | KDM4CS1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |