Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.48 |
| ▸ | KDM5C | P41229 | 7/20 | 0.45 |
| ▸ | KDM4A | O75164 | 6/20 | 0.45 |
| ▸ | KDM6B | O15054 | 3/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.45 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.43 |
| ▸ | KDM4B | O94953 | 4/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.42 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 3/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3206270 | 0.86 | KDM4C (0.40) | KDM4CKDM5CKDM4AKDM6BKDM2A | |
| SCHEMBL1853424 | 0.86 | KDM4E (0.48) | KDM4CKDM5CKDM6BKDM2AKDM3A | |
| SCHEMBL1846891 | 0.82 | S1PR5 (0.53) | S1PR5S1PR4 | |
| SCHEMBL1850872 | 0.81 | KDM4C (0.49) | KDM4CKDM5CKDM4AKDM6BKDM2A | |
| SCHEMBL1852635 | 0.80 | GPR52 (0.57) | KDM4CS1PR5S1PR4 | |
| SCHEMBL1850399 | 0.79 | GPR52 (0.56) | KDM4CKDM5CKDM4AKDM6BKDM2A | |
| SCHEMBL1850820 | 0.79 | MRGPRX4 (0.54) | KDM4CS1PR5S1PR4 | |
| SCHEMBL1849882 | 0.77 | GPR52 (0.57) | KDM4CS1PR5S1PR4 | |
| SCHEMBL1851474 | 0.76 | KDM4E (0.47) | KDM4CKDM5CKDM6BKDM2AKDM3A | |
| SCHEMBL1852370 | 0.76 | GPR52 (0.52) | KDM4CKDM5CKDM4AKDM6BKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |